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Construction of confidence bounds for cost-effective treatments using improved fixed sequence testing strategies

R and FORTRAN code

Paper of Klaus Strassburger and Frank Bretz

The R and FORTRAN codes obtains the critical constant to construct confidence bounds for cost effective treatments as proposed by Strassburger et al. (2004).

The R code is written rather general and can be extended to accomplish more general data dependency structures than considered in the paper.

The FORTRAN implements the analytical expressions given in the paper and is substantially faster than the R code.