Prof. Dr. Frank Bretz
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Statistical Methodology
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novartis.com
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Research Interests
My primary research interests include multiple comparison procedures, dose response experiments and adaptive designs. These topics are frequently encountered in practice and have applications in such different areas as clinical trials, toxicology, biology, physics, etc. In the past I was also interested in multidimensional integration routines to compute probabilities and critical values from multivariate distribution functions as well as in the design and analysis of microarray experiments.
Software
Publications
- Books
- Bretz, F., Hothorn, T., and Westfall, P. (2010) Multiple comparisons using R. CRC Press, Boca Raton. ISBN 978-1-584-88574-0.
- Genz, A. and Bretz, F. (2009) Computation of multivariate normal and t probabilities. Lecture Notes in Statistics, Vol. 195. Springer, Heidelberg. ISBN 978-3-642-01688-2
- Dmitrienko, A., Tamhane, A. and Bretz, F. (2009) Multiple testing problems in pharmaceutical statistics. Chapman & Hall/CRC Biostatistics Series, Boca Raton. ISBN 978-1-584 88984-7
- Benjamini, Y., Bretz, F. and Sarkar, S. (2004) Recent developments in multiple comparison procedures. IMS Lecture Notes - Monograph Series, Vol. 47, Beachwood, Ohio. ISBN 0-940600-63-3
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